The World Most Popular Herbs

Sunday, January 15, 2012

Valerian Health Benefits and Side Effects

Valerian is a perennial flowering plant, in the genus Valeriana, belonging to the family Valerianaceae, native to Europe and parts of Asia. The herb has been used as a sedative and relaxing agent and to treat the liver, the urinary tract, the digestive tract problem, nerve conditions, etc.

Health Benefits
1. Insomnia
In the investigation of the extracts of the roots of valerian (Valeriana officinalis) used for inducing sleep and improving sleep quality, found that valerian might improve sleep quality without producing side effects. Future studies should assess a range of doses of standardized preparations of valerian and include standard measures of sleep quality and safety, according to " Valerian for sleep: a systematic review and meta-analysis" by Bent S, Padula A, Moore D, Patterson M, Mehling W.(1)

2. Anxiety
In a controlled pilot study on the putative anxiolytic effect of valepotriates, found that the valepotriates may have a potential anxiolytic effect on the psychic symptoms of anxiety. However, since the number of subjects per group was very small, the present results must be viewed as preliminary. Thus, further studies addressing this issue are warranted, according to "Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study" by Andreatini R, Sartori VA, Seabra ML, Leite JR.(2)

3. Central nervous system
In the identification of Humans consume a wide range of foods, drugs, and dietary supplements that are derived from plants and which modify the functioning of the central nervous sytem (CNS), indicated that the current evidence for the efficacy of a range of readily available plant-based extracts and chemicals that may improve brain function and which have attracted sufficient research in this regard to reach a conclusion as to their potential effectiveness as nootropics. Many of these candidate phytochemicals/extracts can be grouped by the chemical nature of their potentially active secondary metabolite constituents into alkaloids (caffeine, nicotine), terpenes (ginkgo, ginseng, valerian, Melissa officinalis, sage), and phenolic compounds (curcumin, resveratrol, epigallocatechin-3-gallate, Hypericum perforatum, soy isoflavones), according to "Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function" by Kennedy DO, Wightman EL.(3)

4. Antidepressant effect
In the investigation of the antidepressant effect of dichloromethane extract of Valeriana wallichii patchouli alcohol chemotype, found that The extract demonstrated antidepressant effect and significantly increased the norepinephrine and dopamine levels in forebrain, according to "Antidepressant effect of Valeriana wallichii patchouli alcohol chemotype in mice: Behavioural and biochemical evidence" by Sah SP, Mathela CS, Chopra K.(4)

5. Liver cirrhosis
In the study of the therapeutic effect of the extract of Valeriana jatamansi (family, Valerianaceae) prepared from the dried rhizome of the herb in an animal model of liver cirrhosis and on cell proliferation found that Treatment was found to partially reverse the elevated levels of alkaline phosphatase, γ-glutamyl transferase and selected biochemical markers of hepatic injury including drug-metabolizing enzymes. Histopathology of the hepatic tissue confirmed the therapeutic effect of the extract which corroborated with the biochemical changes. The extract is also reported to ameliorate hepatic cell proliferation in rats injected with thioacetamide. The study has implications in finding a treatment for liver cirrhosis in humans, according to "Valeriana jatamansi partially reverses liver cirrhosis and tissue hyperproliferative response in rat" by Prasad R, Naime M, Routray I, Mahmood A, Khan F, Ali S.(5)

6. Peripheral analgesic effects
In the evaluation of the effect of V. wallichii chemotype (patchouli alcohol) extract (DCME) and essential oil (VPAEO) on experimental models of nociception and to elucidate its possible mechanism of action, found that DCME and VPAEO (40 and 80 mg/kg, p.o.) significantly inhibited the number of writhings as compared to vehicle treated group. None of the doses of DCME and VPAEO exhibited any effect in tail flick model suggesting only peripheral analgesic activity. When studied for mechanism of action in acetic acid induced writhing, subeffective dose of essential oil significantly potentiated the effect of aspirin while no potentiation was seen in case of extract. These data suggest that essential oil VPAEO exerted peripheral analgesic via inhibition of prostaglandin synthesis, accoridng to "Elucidation of possible mechanism of analgesic action of Valeriana wallichii DC chemotype (patchouli alcohol) in experimental animal models" by Sah SP, Mathela CS, Chopra K.(6)

7. Alzheimer's disease
In the investigation of the effects of Valeriana amurensis on the expressions of P-APP,A4,1 and Caspase-3 of cortical neurons and hippocampus neurons in in Alzheimer's disease model rats' brain, found that The 50% ethanol extracts of macroporous resin group from the roots and rhizomes of Valeriana amurensis can decrease the expressions of beta-APP, Abeta(1-40), and Caspase-3, to inhibit the formation of senile plaques and neurofibrillary tangles in Alzheimer's disease model rats' brain, and decrease cell fate of cortical neurons and hippocampus neurons in in Alzheimer's disease model rats' brain, according to "[Effects of Valeriana amurensis on the expressions of beta-APP, Abeta(1-40) and caspase-3 in Alzheimer's disease model rat's brain].[Article in Chinese]" by Zuo YM, Zhang ZL, Wang QH, Xie N, Kuang HX.(7)

8. Antioxidant activity
In the classification of V. officinalis extracts and its antioxidant properties against iron in hippocampal neurons in vitro, found that The effect of V. officinalis in deoxyribose degradation and reactive oxygen species (ROS) production was also investigated. In brain homogenates, V. officinalis inhibited thiobarbituric acid reactive substances induced by all pro-oxidants tested in a concentration dependent manner. Similarly, V. officinalis caused a significant decrease on the LPO in cerebral cortex and in deoxyribose degradation. QA-induced ROS production in cortical slices was also significantly reduced by V. officinalis, according to "In vitro antioxidant activity of Valeriana officinalis against different neurotoxic agents" by Sudati JH, Fachinetto R, Pereira RP, Boligon AA, Athayde ML, Soares FA, de Vargas Barbosa NB, Rocha JB.(8)

9. Anticonvulsant effect
In the study the effect of valerian extracts on an experimental model of temporal lobe epilepsy (TLE), the results showed significant anticonvulsant effect for aqueous but not PE extract of valerian. Moreover, CPT as a selective adenosine A(1) receptor antagonist decreased the anticonvulsant effect of valerian aqueous extract, according to " Anticonvulsant effect of aqueous extract of Valeriana officinalis in amygdala-kindled rats: possible involvement of adenosine" by Rezvani ME, Roohbakhsh A, Allahtavakoli M, Shamsizadeh A.(9)

10. Relaxing effects
In the investigation of the relaxing effects of Valeriana officinalis L. (Valerianaceae) on human uterine muscle found that valerian extracts and valepotriates inhibited uterine contractility in a concentration-dependent manner. Pretreatment with either atenolol or indometacin did not affect the uterine responses to valerian extracts. Valerian extract reduced the maximal contractile response induced by acetylcholine, phenylephrine and histamine independent of the stimulus, according to "Relaxing effects of Valeriana officinalis extracts on isolated human non-pregnant uterine muscle" by Occhiuto F, Pino A, Palumbo DR, Samperi S, De Pasquale R, Sturlese E, Circosta C.(10)

11. Etc.

Side effects
1. Do not use the herb in Newborn, children or if you are pregnant or breast feeding without approval from the related field specialist
2. Valerian may interact with other medicine, including drugs suppress the central nervous system and include Valium, Xanax, Klonopin, Libruim, etc.
3. Etc.

Healthy Happy Herbs
A Beginner's Guide To Herbs And
Herb Gardening, Step by step

For More healthy food recipes visit http://theworldmosthealthyfoodsrecipes.blogspot.com/2011/10/workd-most-healthy-foods-recipes-index.html

For the world most healthy foods visit http://healthy-foods-index.blogspot.com/2011/03/healthy-foods-list.html

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/17145239
(2) http://www.ncbi.nlm.nih.gov/pubmed/12410546
(3) http://www.ncbi.nlm.nih.gov/pubmed/22211188
(4) http://www.ncbi.nlm.nih.gov/pubmed/21354297
(5) http://www.ncbi.nlm.nih.gov/pubmed/21225006
(6) http://www.ncbi.nlm.nih.gov/pubmed/21046983
(7) http://www.ncbi.nlm.nih.gov/pubmed/20575418
(8) http://www.ncbi.nlm.nih.gov/pubmed/19191025
(9) http://www.ncbi.nlm.nih.gov/pubmed/19900527
(10) http://www.ncbi.nlm.nih.gov/pubmed/19178774

Arctostaphylos uva-ursi Health Benefits and Side Effects

Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to the northern North America, Asia and Europe. The herb has been used in traditional medicine as diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stone, pelvic pain, etc.

Health Benefits
1. Diuretic effect
In the investigation of the diuretic effect of aqueous extracts of Sambucus nigra and Arctostaphylos uva-ursi and hydroalcohol extracts of Orthosiphon stamineus and Hieracium pilosella, found that pharmacological evaluation revealed that they led to an increase in urine flow. Urinary sodium excretion in rats was increased with O. stamineus and S. nigra, according to "Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rat" by Beaux D, Fleurentin J, Mortier F.(1)

2. Bladder cancer
In the investigation of Arbutin is a glycosylated hydroquinone extracted from the bearberry plant (Arctostaphylos species) and its effects on TCCSUP human bladder carcinoma cell proliferation, found that arbutin significantly decreased TCCSUP cell proliferation in a concentration- and time-dependent manner. Furthermore, cell cycle analysis revealed that arbutin strongly disrupted the cell cycle in a time-dependent manner, according to "Arbutin inhibits TCCSUP human bladder cancer cell proliferation via up-regulation of p21" by Li H, Jeong YM, Kim SY, Kim MK, Kim DS.(2)

3. Anti microbial effects
In the determination of anti microbial effects of standard ATCC microbial strains used for drug control: S. aureus, E. coli, P. aeruginosa and C. albicans, found that Uversan 50 mg tabl. (arbutine from Arctostaphylos uva ursi). S. aureus strain was susceptible to the most of the drugs listed above. The lowest inhibitory concentration was found for sertraline and hipericine (0.16 and 0.075 mg/mL, respectively), according to "Examination of antimicrobial activity of selected non-antibiotic drugs" by Kruszewska H, Zareba T, Tyski S.(3)

4. Urinary excretion
In the study on 3 volunteers the time-dependent renal excretion of arbutin metabolites 2, 5 and 6 after ingestion of an aqueous bearberry leaf extract, found that More than half of the administered dose of arbutin was excreted within 4 hours mainly in form of the metabolites 2 and 6 and more than 75 % of the total applied arbutin was excreted within 24 h. The elimination of 5 was negligible in 2 out of 3 volunteers. The excretion of this metabolite in the third test person reached 5.6 % of the total administered arbutin dose. The preliminary pharmacokinetic results confirm that renal elimination of toxicologically critical concentrations of the metabolite 5 will not be expected, according to "Urinary excretion of arbutin metabolites after oral administration of bearberry leaf extracts" by Quintus J, Kovar KA, Link P, Hamacher H.(4)

5. Antiseptic properties
In comparison to incubation with glusulase the E. coli-suspension resulted in a 2.3 fold higher increase in free hydroquinone, found that when separating bacteria from the urine, the hydroquinone concentration in bacteria was 20 fold higher than in the supernatant, according to "Bacterial deconjugation of arbutin by Escherichia coli" by Siegers C, Bodinet C, Ali SS, Siegers CP.(5)

6. Antioxidant effects
In the determination of the antioxidant properties of some plants, including Arctostaphylos uva-ursi, found that The antioxidant effect was evaluated with regard to single dose of plant extracts and their concentration in human organism. The effect decreases in the following consequence: Hypericum perforatum > Potentilla erectra > Ledum palustre > Plantago major > Salvia officinalis > Chamomilla recutita > Arctostaphylos uva, according to "[Antioxidant properties of plant extracts].[Article in Russian]" by Bol'shakova IV, Lozovskaia EL, Sapezhinskiĭ II.(6)

7. Antiallergic and antiinflammatory activities
In the identification of the effects of water extract (UW-ext) from the leaf of Arctostaphylos uva-ursi (L.) Spreng (Bearberry leaf) on the antiallergic and antiinflammatory activities, found that One or 2% UW-ext ointment did not inhibit the ear swelling by picryl chloride-induced contact dermatitis (PC-CD) and carrageenin-induced paw edema. UW-ext augmented the inhibitory effect of dexamethasone ointment (0.005 or 0.025%) on these allergic and inflammatory models, but not the side effect of it. These results suggest that Bearberry leaf increases the inhibitory effect of dexamethasone on the allergic and inflammatory models, accoridng to "[Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. V. Effect of water extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) on the antiallergic and antiinflammatory activities of dexamethasone ointment].[Article in Japanese]" by Matsuda H, Nakamura S, Tanaka T, Kubo M(7)

8. Edema and Arthritis
In the examination of the combined effect of arbutin isolated from the leaves of Arctostaphylos uva-ursi (L.) Spreng. (Bearberry leaf) and indomethacin on Type IV allergic reaction-induced immuno-inflammation, carrageenin-induced edema and adjuvant-induced arthritis, found that
arbutin at dose of 50 mg/kg 24 h after the application rapidly decreased the swelling of PC-CD. Arbutin (p.o.) plus indomethacin (s.c.) showed inhibitory effect on the swelling of PC-CD and SRBC-DTH stronger than that of indomethacin alone. When arbutin (p.o.) and indomethacin (s.c.) in a given portion were simultaneously administered, the inhibitory effect was more potent than that of indomethacin alone in both carrageenin-induced edema and adjuvant-induced arthritis, according to "[Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. III. Combined effect of arbutin and indomethacin on immuno-inflammation].[Article in Japanese] by Matsuda H, Tanaka T, Kubo M.(8)

9. Diabetes
In the examination of Seven plants and a herbal mixture used for traditional treatment of diabetes in streptozotocin diabetic mice, found that bearberry, mistletoe and tarragon retarded the body weight loss but none of the eight treatments significantly altered plasma glucose or insulin concentrations. These studies suggest that bearberry, golden seal, mistletoe and tarragon may counter some of the symptoms of streptozotocin diabetes without, however, affecting glycemic control, according to "Evaluation of traditional plant treatments for diabetes: studies in streptozotocin diabetic mice" by Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR.(9)

10. Etc.

Usnea Health Benefits and Side Effects

Usnea is a symbiosis of a fungus and an alga, generally growth hanging from tree branches, a genus Usnea, belonging to the family Parmeliaceae. The herb has been used in tradtional medicine to enhance immune function, relieve sore throat, bronchitis, cold & flu, infection, to treat indigestion, etc.

Health Benefits
1. Antioxidative and hepatoprotective activity
In the demonstration of antioxidative and hepatoprotective activity of a cultured lichen Usnea ghattensis, found that The cultured lichen extract also showed hepatoprotection against ethanol-induced toxicity in the mice liver slice culture model by a significant decrease in the antioxidant enzymes, glutathione peroxidase, catalase, and superoxide dismutase, along with a decrease in lipid peroxidation and lactate dehydrogenase release, according to "Antioxidant and hepatoprotective activity of a lichen Usnea ghattensis in vitro" by Verma N, Behera BC, Makhija U.(1)

2. Antioxidant and antibacterial activities

In the investigation of methanol extract in the preventiopn of lipid peroxidation by 87% followed by 65% in Trolox at 20 microg/ml, found that In addition, these extracts were inhibitory against Bacillus licheniformis, Bacillus megaterium, Bacillus subtilis and Staphylococcus aureus with MIC values of 5-10 microg/ml, according to "Antioxidant and antibacterial activities of lichen Usnea ghattensis in vitro" by Behera BC, Verma N, Sonone A, Makhija U.(2)

3. Antimicrobial activity
In the determination of the usnic acid amounts in acetone extracts by HPLC of six species of lichens, such as Usnea florida, Usnea barbata, Usnea longissima, Usnea rigida, Usnea hirta and Usnea subflorida, found that antimicrobial activities of these extracts were determined against Escherichia coli (ATCC 35218), Enterococcus faecalis (RSKK 508), Proteus mirabilis (Pasteur Ens. 235), Staphylococcus aureus, Bacillus subtilis and Bacillus megaterium. It was shown that with increasing amount of usnic acid, the antimicrobial activity increased. Usnic acid contents of Usnea species varied between 0.22-6.49% of dry weight, according to "Identification and quantitation of usnic acid from the lichen Usnea species of Anatolia and antimicrobial activity" by Cansaran D, Kahya D, Yurdakulola E, Atakol O.(3)

4. Antiplatelet and antithrombotic activities
In the investigation of the antiplatelet and antithrombotic activities of a methanol extract of a medicinal lichen, Usnea longissima, found that the antithrombotic activity of U. longissima extract might be due to antiplatelet activity rather than anticoagulant activity, according to "Antiplatelet and antithrombotic activities of methanol extract of Usnea longissima" by Lee KA, Kim MS.(4)

5. Gastroprotective and antioxidant effects
In the determination of Usnea longissima, a medicinal lichen of Anatolia (Turkey), used in the treatment of gastric ulcer in local folk medicine in rat, found that he gastric lesions were significantly reduced by all doses of UA as compared with the indomethacin (25 mg/kg body weight) treated group. In the stomach tissues of treated animals, the in vivo antioxidant levels were evaluated. The administration of indomethacin caused a significant decrease in the levels of superoxide dismutase (SOD), glutathione peroxidase (GPx) and reduced glutathione (GSH), and an increase in the lipid peroxidation (LPO) level (p < 0.05). The administration of all doses of UA reversed the trend, inducing a significant increase of SOD, GSH and GPx levels and a reduction in LPO level in tissues, according to "Gastroprotective and antioxidant effects of usnic acid on indomethacin-induced gastric ulcer in rats" by Odabasoglu F, Cakir A, Suleyman H, Aslan A, Bayir Y, Halici M, Kazaz C.(5)

6. Skin wound healing
In the study of the effects of sodium usnic acid on proliferation of fibroblasts and skin wound healing, found that Sodium usnic acid can accelerate skin wound healing, the effects was not by stimulating proliferation of fibroblasts. according to "[The study on skin wound healing promoting action of sodium usnic acid].[Article in Chinese]" by Jin J, Dong Y, He L.(6)

7. Antineoplastic activity
In the determination of Different fractions, isolated from the lichen Usnea fasciata, analyzed by PC, TLC, and RP-HPLC for the effect on Antineoplastic activity, found that Fractions containing usnic acid, as well as those containing isolichenin, showed moderate activity against sarcoma 180 and Ehrlich tumor cells. High antitumoral activity, near 90% inhibition, was found associated with the fraction containing raffinose, according to "Analysis of Usnea fasciata crude extracts with antineoplastic activity" by Periera EC, Nascimento SC, Lima RC, Silva NH, Oliveira AF, Bandeira E, Boitard M, Beriel H, Vicente C, Legaz ME.(7)

8. Etc.

Side effects

1. Overdoses may be toxic (a)

2. Please consult with the related field specialist before applying the herb to new born, children, or if yopu are pregnant or breast feeding.
2. The herb may cause allergic effect (b)

Healthy Happy Herbs
A Beginner's Guide To Herbs And
Herb Gardening, Step by step

For More healthy food recipes visit http://theworldmosthealthyfoodsrecipes.blogspot.com/2011/10/workd-most-healthy-foods-recipes-index.html

For the world most healthy foods visit http://healthy-foods-index.blogspot.com/2011/03/healthy-foods-list.html

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19034791
(b) http://www.ncbi.nlm.nih.gov/pubmed/3568642
(1) http://www.ncbi.nlm.nih.gov/pubmed/18975145
(2) http://www.ncbi.nlm.nih.gov/pubmed/16132842
(3) http://www.ncbi.nlm.nih.gov/pubmed/17294685
(4) http://www.ncbi.nlm.nih.gov/pubmed/16372374
(5) http://www.ncbi.nlm.nih.gov/pubmed/16169175
(6) http://www.ncbi.nlm.nih.gov/pubmed/15981883
(7) http://www.ncbi.nlm.nih.gov/pubmed/7660383

Turmeric (Curcuma longa) Health Benefits and Side Effects

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia. The herb has been used in trditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

Health Benefits
1. Pancreatic cancer
In the study of the cytotoxic effect of Turmeric Force (TF), a supercritical and hydroethanolic extracted from turmeric, alone and in combination with gemcitabine in two pancreatic carcinoma cell lines (BxPC3 and Panc-1), found that TF induced cell death in 96% of the cells at 50 microg/ml. The combination of gemcitabine and TF was synergistic with IC90 levels achieved in both pancreatic cancer cell lines at lower concentrations. CalcuSyn analysis of cytotoxicity data showed that the Gemcitabine + Turmeric Force combination has strong synergism with combination index (CI) values of 0.050 and 0.183 in BxPC3 and Panc-1 lines, respectively at IC50 level, according to "Potentiation of gemcitabine by Turmeric Force in pancreatic cancer cell lines" by Ramachandran C, Resek AP, Escalon E, Aviram A, Melnick SJ.(1)

2. Cancer Therapy
In the investigation of the effect of an ethanol extract of turmeric ("Curcuma longa") as well as an ointment of curcumin (its active ingredient) in relieving symptoms in patients with external cancerous lesions, found that Reduction in smell were noted in 90% of the cases and reduction in itching in almost all cases. Dry lesions were observed in 70% of the cases, and a small number of patients (10%) had a reduction in lesion size and pain. In many patients the effect continued for several months. An adverse reaction was noticed in only one of the 62 patients evaluated, according to" Turmeric and curcumin as topical agents in cancer therapy" by Kuttan R, Sudheeran PC, Josph CD.(2)

3. Anti cancer effects
In assessment of the anticancer activity of the rhizomes of turmeric, in vitro, using tissue culture methods and in vivo in mice, found that Cytotoxic effect was found within 30 min at room temperature (30 degrees C). The active constituent was found to be 'curcumin' which showed cytotoxicity to lymphocytes and Dalton's lymphoma cells at a concentration of 4 micrograms/ml. Initial experiments indicated that turmeric extract and curcumin reduced the development of animal tumours, according to "Potential anticancer activity of turmeric (Curcuma longa)" by Kuttan R, Bhanumathy P, Nirmala K, George MC.(3)

4. Antifungal activity
In the determination of the urmeric oil and curcumin, isolated from Curcuma longa L., effects against fifteen isolates of dermatophytes, four isolates of pathogenic molds and six isolates of yeasts, found that turmeric oil (dilution 1:80) was applied by dermal application on the 7th day following dermatophytosis induction with Trichophyton rubrum. An improvement in lesions was observed in 2-5 days and the lesions disappeared 6-7 days after the application of turmeric oil, accoridng to "Antifungal activity of turmeric oil extracted from Curcuma longa (Zingiberaceae)" by Apisariyakul A, Vanittanakom N, Buddhasukh D.(4)

5. Anti prostate diseases
In the examination of the use of turmeric, derived from the root of the plant curcuma longa, for the treatment of various diseases in Ayurveda and in Traditional Chinese Medicine for thousands of years, indicated that extensive research over the last decade has indicated that this polyphenol can both prevent and treat prostatic diseases, acccording to "[Curcumin in the treatment of prostatic diseases].[Article in Chinese]" by Chen ZQ, Mo ZN.(5)

6. Anti inflammatory effects
In a systematic review of the literature was to summarize the literature on the safety and anti-inflammatory activity of curcumin, found that curcumin has been demonstrated to be safe in six human trials and has demonstrated anti-inflammatory activity. It may exert its anti-inflammatory activity by inhibition of a number of different molecules that play a role in inflammation, according to "Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa)" by Chainani-Wu N (6)

7. Antioxidants
In the reseach of a literature search (PubMed) of almost 1500 papers dealing with curcumin, most from recent years, with ll available abstracts were read and pproximately 300 full papers were reviewed, found that curcumin, a component of turmeric, has been shown to be non-toxic, to have antioxidant activity, and to inhibit such mediators of inflammation as NFkappaB, cyclooxygenase-2 (COX-2), lipooxygenase (LOX), and inducible nitric oxide synthase (iNOS). Significant preventive and/or curative effects have been observed in experimental animal models of a number of diseases, including arteriosclerosis, cancer, diabetes, respiratory, hepatic, pancreatic, intestinal and gastric diseases, neurodegenerative and eye diseases, "Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases" by Bengmark S.(7)

8. Neuroprotective effect
In the finding of the A Potential Neuroprotective Agent in treating Parkinson's Disease, found that curcumin exhibits antioxidant, anti-inflammatory and anti-cancer properties, crosses the blood-brain barrier and is neuroprotective in neurological disorders. Several studies in different experimental models of PD strongly support the clinical application of curcumin in PD. The current review explores the therapeutic potential of curcumin in PD, according to "Curcumin: A Potential Neuroprotective Agent in Parkinson's Disease" by Mythri RB, Bharath MS.(8)

9. Antiarthritic efficacy
In the determination of the antiarthritic efficacy and mechanism of action of a well-characterized turmeric extract using an animal model of rheumatoid arthritis (RA), found that a turmeric fraction depleted of essential oils profoundly inhibited joint inflammation and periarticular joint destruction in a dose-dependent manner. In vivo treatment prevented local activation of NF-kappaB and the subsequent expression of NF-kappaB-regulated genes mediating joint inflammation and destruction, including chemokines, cyclooxygenase 2, and RANKL, according to "Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis" by Funk JL, Frye JB, Oyarzo JN, Kuscuoglu N, Wilson J, McCaffrey G, Stafford G, Chen G, Lantz RC, Jolad SD, Sólyom AM, Kiela PR, Timmermann BN.(9)

10. Gastrointestinal diseases
In the exporation more systematically in various diseases of curcumin's therapeutic promise,
indicated that curcumin may be particularly suited to be developed to treat gastrointestinal diseases. This review summarizes some of the current literature of curcumin's anti-inflammatory, anti-oxidant and anti-cancer potential in inflammatory bowel diseases, hepatic fibrosis and gastrointestinal cancers, according to "Therapeutic potential of curcumin in gastrointestinal diseases" by Rajasekaran SA.(10)

11. Diabetes
In identification of turmerin, a water-soluble peptide in turmeric rhizomes,and its inhibitory potential against glucosidase and its antioxidant (AO) capacity, indicated that Turmerin showed good DPPH (IC(50) = 29 µg mL(-1)) and superoxide (IC(50) = 48 µg mL(-1)) and moderate ABTS (IC(50) = 83 µg mL(-1)) radical scavenging and Fe(II) chelation (IC(50) = 101 µg mL(-1)) capacities. The inhibitory potential showed by turmerin against enzymes linked to type 2 diabetes, as well as its moderate AO capacity, could rationalise the traditional usage of turmeric rhizome preparations against diabetes, according to "Turmerin, the antioxidant protein from turmeric (Curcuma longa) exhibits antihyperglycaemic effects" by Lekshmi PC, Arimboor R, Raghu KG, Menon AN.(11)

12. Wound healing
In the testing the efefct of wound healing of fresh turmeric (Curcuma longa) paste in a preclinical study in an animal model, found that Only tensile strength was measured on day 14 of treatment. It was observed that the wound healing was statistically significantly faster (P < .01) in both treatment groups compared to the control group, according to "Turmeric (Curcuma longa) rhizome paste and honey show similar wound healing potential: a preclinical study in rabbits" by Kundu S, Biswas TK, Das P, Kumar S, De DK.(12)

13. Etc.

Side effects
1. Overdose may cause gastrointestinal discomfort such as nausea and diarrhea and liver damage.
2. Topical use may be allergic to skin such irritation to certain peoples
3. Do not use the herb in new born, children or if you are pregnant and breast feeding without approval from the related field specialist.
4. Etc.

Healthy Happy Herbs
A Beginner's Guide To Herbs And
Herb Gardening, Step by step

For More healthy food recipes visit http://theworldmosthealthyfoodsrecipes.blogspot.com/2011/10/workd-most-healthy-foods-recipes-index.html

For the world most healthy foods visit http://healthy-foods-index.blogspot.com/2011/03/healthy-foods-list.html
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20428806
(2) http://www.ncbi.nlm.nih.gov/pubmed/2435036
(3) http://www.ncbi.nlm.nih.gov/pubmed/4075289
(4) http://www.ncbi.nlm.nih.gov/pubmed/8824742
(5) http://www.ncbi.nlm.nih.gov/pubmed/18297817
(6) http://www.ncbi.nlm.nih.gov/pubmed/12676044
(7) http://www.ncbi.nlm.nih.gov/pubmed/16387899
(8) http://www.ncbi.nlm.nih.gov/pubmed/22211691
(9) http://www.ncbi.nlm.nih.gov/pubmed/17075840
(10) http://www.ncbi.nlm.nih.gov/pubmed/21607160
(11) http://www.ncbi.nlm.nih.gov/pubmed/21972920
(12) http://www.ncbi.nlm.nih.gov/pubmed/16286372

Triphala Health Benefits and Side Effects

Triphala is an Ayurvedic fomula consisting of equal parts of Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellirica), and Haritaki (Terminalia chebula) of myrobalans. The herb has been used in traditional medicine to treat constipation, tonify colon, gastrointestinal tract, balance digestive system, cholesterol, enhance circulation, uterine health, etc.

Health Benefits
1. Antibacterial efficacy
In the assessment ofthe antibacterial efficacy of triphala against salivary mutans streptococci in comparison with the 'gold standard' chlorhexidine, found that The antimicrobial action of triphala against mutans streptococci closely parallels that of chlorhexidine. It does not have the side effects commonly associated with chlorhexidine and is cost effective, according to "Assessment of antibacterial efficacy of triphala against mutans streptococci - a randomised control trial" by Srinagesh J, Pushpanjali K.(1)

2. Prostate cancer
In the identification of gallic acid (GA), a major bioactive cytotoxic constituent of a polyherbal Ayurvedic formulation - triphala (TPL) and its effect on (AR)(+) LNCaP prostate cancer and normal epithelial cells, found that TPL contains 40% unidentified polyphenolic acids, of which 2.4% comprised GA. GA induced severe morphological alterations and was about 3-fold more cytotoxic towards cancer cells than TPL. This activity increased further in the presence of dihydrotestosterone. GA toxicity on normal cells was low at 72 h. Combination of GA with flutamide caused higher toxicity to cancer cells than either of the compounds alone, according to "Differential cytotoxicity of triphala and its phenolic constituent gallic acid on human prostate cancer LNCap and normal cells" by Russell LH Jr, Mazzio E, Badisa RB, Zhu ZP, Agharahimi M, Millington DJ, Goodman CB.(2)

3. Dental health
In the study of the effects of a mouthwash prepared with Triphala on dental plaque, gingival inflammation, and microbial growth and compare it with commercially available Chlorhexidine mouthwash, found that in the inhibitory effect on microbial counts except Lactobacillus where Triphala had shown better results than Chlorhexidine. It was concluded that there was no significant difference between the Triphala and the Chlorhexidine mouthwash, according to "The effect of Triphala and Chlorhexidine mouthwash on dental plaque, gingival inflammation, and microbial growth" by Bajaj N, Tandon S.(3)

4. Anticataract effects
In the evaluation of evaluation of riphala (TP) is composed of Emblica officinalis, Terminalia chebula, and Terminalia belerica anticataract potential in vitro and in vivo in a selenite-induced experimental model of cataract, found that in vivo TF 25mg/kg developed only 20% nuclear cataract as compared to 100% in control. TP prevents or retards experimental selenite-induced cataract. This effect may be due to antioxidant activity. Further studies are warranted to explore its role in human cataract, according to "Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies" by Gupta SK, Kalaiselvan V, Srivastava S, Agrawal SS, Saxena R.(4)

5. Antibacterial, wound healing, and antioxidant activities in would healing
In the indentification of the Triphala extract (10% w/w) in vivo on wound healing on infected rat model by rate of healing, bacterial count, biochemical analysis, and expression of matrix metalloproteinases, found that results showed the antibacterial, wound healing, and antioxidant activities of Triphala ointment, necessary for the management of infected wounds. Active principles of the Triphala may be further evaluated and used as an excellent therapeutic formulation for infected wounds, according to "Triphala promotes healing of infected full-thickness dermal wound" by Kumar MS, Kirubanandan S, Sripriya R, Sehgal PK.(5)

6. Cancers prevention and treatment
In the review of Triphala, an antioxidant-rich herbal formulation and its effects as colon cleanser, digestive, diuretic, and laxative, indicated that Experimental studies in the past decade have shown that Triphala is useful in the prevention of cancer and that it also possesses antineoplastic, radioprotective and chemoprotective effects, according to "Triphala, Ayurvedic formulation for treating and preventing cancer: a review" by Baliga MS.(6)

7. Antioxidants
In the assessment of The aqueous extract of the fruits of Emblica officinalis (T1), Terminalia chebula (T2) and Terminalia belerica (T3) and their equiproportional mixture triphala for their in vitro antioxidant activity, indicated that the extracts were found to possess the ability to scavenge free radicals such as DPPH and superoxide. As the phenolic compounds present in these extracts are mostly responsible for their radical scavenging activity, the total phenolic contents present in these extracts were determined and expressed in terms of gallic acid equivalents and were found to vary from 33% to 44%, according to "In vitro antioxidant studies and free radical reactions of triphala, an ayurvedic formulation and its constituents" by Naik GH, Priyadarsini KI, Bhagirathi RG, Mishra B, Mishra KP, Banavalikar MM, Mohan H.(7)

8. Anti-ulcer activity
In the study of the efficacy of the polyherbal formulation NR-ANX-C (composed of the extracts from Withania somnifera, Camellia sinensis, Ocimum sanctum, shilajith and triphala) and its antioxidant potential in terms of protection from lipid peroxidation and the antiulcer activity, found that R-ANX-C (25 and 50 mg/kg) was more efficacious than ranitidine in reducing ulcer index in both the models. At the highest dose tested (50 mg/kg), NR-ANX-C was comparable to omeprazole in preventing ulcer formation in the pyloric ligature model. NR-ANX-C showed a dose- dependent decrease in gastric juice volume and total acidity in both the models. A dose-dependent increase in gastric pH and total adherent gastric mucus was also seen in NR-ANX-C treated groups. The extent of lipid peroxidation was also reduced in the test drug treated groups, according to "Evaluation of the anti-ulcer activity of NR-ANX-C (a polyherbal formulation) in aspirin & pyloric ligature induced gastric ulcers in albino rats" by Nair V, Arjuman A, Gopalakrishna HN, Dorababu P, Mirshad PV, Bhargavan D, Chatterji D.(8)

9. Hypolipidemic activity
In the investigation of Hypolipidemic activity of haritaki (terminalia chebula) in atherogenic diet induced hyperlipidemic rat, found that Haritaki was found to possess significant hypolipidemic activity. The results also suggest that Haritaki at 1.05 and 2.10 mg/kg b.wt. concentrations are an excellent lipid-lowering agent, according to "Hypolipidemic activity of haritaki (terminalia chebula) in atherogenic diet induced hyperlipidemic rats" by Maruthappan V, Shree KS.(9)

10. Anti-Salmonella activity
In the research of Fruits of T. belerica extract with petroleum ether, chloroform, acetone, alcohol and water and its effect gainst Salmonella typhi and Salmonella typhimurium , found that that aqueous extract of T. belerica was bactericidal at high concentrations where as low concentrations showed bacteriostatic property. In vitro cellular toxicity studies showed no cyto-toxicity associated with T. belerica extracts. Pretreatment of mice with aqueous extract of T. belerica conferred protection against experimental Salmonellosis and 100% survival of animals has been reported when challenged with lethal doses of S. typhimurium, according to "Anti-Salmonella activity of Terminalia belerica: in vitro and in vivo studies" by

Madani A, Jain SK.(10)

11. Anti bacteria infection
In the study of the effect of phytochemical (phenolic, flavonoid and carotenoid) and antibacterial activities of aqueous and ethanol extracts of Triphala and its individual components (Terminalia chebula, Terminalia belerica and Emblica officinalis) against certain bacterial isolates (Pseudomonas aeruginosa, Klebsiella pneumoniae, Shigella sonnei, S. flexneri, Staphylococcus aureus, Vibrio cholerae, Salmonella paratyphi-B, Escherichia coli, Enterococcus faecalis, Salmonella typhi) obtained from HIV infected patients, found that most of the bacterial isolates were inhibited by the ethanol and aqueous extracts of T. chebula followed by T. belerica and E. officinalis by both disk diffusion and MIC methods, according to "Evaluation of the growth inhibitory activities of Triphala against common bacterial isolates from HIV infected patients" by Srikumar R, Parthasarathy NJ, Shankar EM, Manikandan S, Vijayakumar R, Thangaraj R, Vijayananth K, Sheeladevi R, Rao UA.(11)

12. Pancreatic tumor
In the elucidation of the molecular mechanism of Triphala against human pancreatic cancer in the cellular and in vivo model, found that Triphala is effective in inhibiting the growth of human pancreatic cancer cells in both cellular and in vivo model. Our data also suggests that the growth inhibitory effects of Triphala is mediated by the activation of ERK and p53 and shows potential for the treatment and/or prevention of human pancreatic cancer, according to "Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis" by Shi Y, Sahu RP, Srivastava SK.(12)

13. Gouty arthritis
In the investigation of the anti-arthritic effect of Triphala in the paw volume, lysosomal enzyme activities, lipid peroxidation, anti-oxidant status and inflammatory mediator TNF-alpha in control and monosodium urate crystal-induced mice, found that Triphala treatment (1 gm/kg/b.w. orally) significantly inhibited the paw volume and the levels of lysosomal enzymes, lipid peroxidation and inflammatory mediator tumour necrosis factor-alpha; however the anti-oxidant status was found to be increased in plasma, liver and spleen of monosodium urate crystal-induced mice when compared to control mice. In addition, beta-glucuronidase and lactate dehydrogenase level were reduced in Triphala (100 microg/ml) treated monosodium urate crystal-incubated polymorphonuclear leucocytes. In conclusion, the results obtained clearly indicated that Triphala exerted a strong anti-inflammatory effect against gouty arthritis, according to "An in vivo and in vitro potential of Indian ayurvedic herbal formulation Triphala on experimental gouty arthritis in mice" by Sabina EP, Rasool M.(13)

14. Etc.

Tea Tree oil Health Benefits and Side Effects

Rea Tree oil is an essential oil with pale yellow color made from the leaves of the Narrow-leaved Tea-tree which is in the genus belonging to the family Myrtaceae, native to the northeast coast of New South Wales, Australia. The herb has been used in the traditional medicine as topical to treat acne, fungal infections, parasites, bacteria infection, relieve pain, etc.

Health Benefits
1. Mild to moderate acne vulgaris
In the determination of the efficacy of 5% tea tree oil in mild to moderate acne vulgaris, found that There was a significant difference between tea tree oil gel and placebo in the improvement of the TLC and also regarding improvement of the ASI. In terms of TLC and ASI, tea tree oil gel was 3.55 times and 5.75 times more effective than placebo respectively. Side-effects with both groups were relatively similar and tolerable and suggested that topical 5% tea tree oil is an effective treatment for mild to moderate acne vulgaris, according to "The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study" by Enshaieh S, Jooya A, Siadat AH, Iraji F.(1)

2. Acne
In the classification of plant extracts and isolated compounds, used increasingly in cosmetics and food supplements to improve skin conditions, indicated that Green tea extract and tea tree oil have been investigated in the treatment of acne. ..., according to "Which plant for which skin disease? Part 1: Atopic dermatitis, psoriasis, acne, condyloma and herpes simplex.[Article in English, German]" by Reuter J, Wölfle U, Weckesser S, Schempp C.(2)

3. Skin inflammation
In the investigation of the anti-inflammatory properties of tea tree oil on histamine-induced weal and flare, found that application of liquid paraffin had no significant effect on histamine-induced weal and flare. There was also no difference in mean flare area between control arms and those on which tea tree oil was applied. However, mean weal volume significantly decreased after tea tree oil application (10 min after tea tree oil application, P = 0.0004, Mann-Whitney U-test), according to "Tea tree oil reduces histamine-induced skin inflammation" by Koh KJ, Pearce AL, Marshman G, Finlay-Jones JJ, Hart PH.(3)

4. Edema
In the evaluation of the effect of topically applied tea tree oil (TTO) on histamine-induced oedema in the ears of mice, found that topical application of TTO, and in particular terpinen-4-ol, may be effective in controlling histamine-induced oedema often associated with Type I allergic immediate hypersensitivities, according to "Tea tree oil reduces histamine-induced oedema in murine ears" by Brand C, Townley SL, Finlay-Jones JJ, Hart PH.(4)

5. Anti tumors
In the examination the anticancer activity of Melaleuca alternifolia (tea tree) oil (TTO) in vitro and its major active terpene component, terpinen-4-ol, against two aggressive murine tumour cell lines, AE17 mesothelioma and B16 melanoma, found that TTO and terpinen-4-ol had significant anti-proliferative activity against two tumour cell lines. Moreover, the identification of primary necrotic cell death and cell cycle arrest of the aggressive tumour cells highlights the potential anticancer activity of TTO and terpinen-4-ol., according to "Induction of necrosis and cell cycle arrest in murine cancer cell lines by Melaleuca alternifolia (tea tree) oil and terpinen-4-ol" by Greay SJ, Ireland DJ, Kissick HT, Levy A, Beilharz MW, Riley TV, Carson CF.(5)

6. Tinea pedis
In the identification of tea tree oil (an essential oil derived primarily from the Australian native Melaleuca alternifolia) and its efficacy in fungal infections, found that tea tree oil cream (10% w/w) appears to reduce the symptomatology of tinea pedis as effectively as tolnaftate 1% but is no more effective than placebo in achieving a mycological cure. This may be the basis for the popular use of tea tree oil in the treatment of tinea pedis, according to "Tea tree oil in the treatment of tinea pedis" by Tong MM, Altman PM, Barnetson RS.(6)

7. Anti microbial effects
In the demonstration of Melaleuca alternifolia oil (tea tree oil) and its promising efficacy in treating these infections, found that tea tree oil has been effective as an adjunctive therapy in treating osteomyelitis and infected chronic wounds in case studies and small clinical trials, according to "Staphylococcus aureus and wounds: a review of tea tree oil as a promising antimicrobial" by Halcón L, Milkus K.(7)

8. Ocular itching
In the assessment of twenty-four patients with ocular itching and ocular Demodex were treated with chlortetracycline hydrochloride eye ointment lid massage for 4 weeks and then treatment was switched to TTOO for another 4 weeks, found that after 4 weeks of chlortetracycline hydrochloride eye ointment treatment, little changes were observed regarding itching and Demodex counts in all patients (P > 0.05). In contrast, after 5% TTOO treatment, 16 patients were totally free of itching and the remaining 8 patients had different degrees of relief (P < 0.01). The Demodex count decreased to 0.7 ± 0.8 for total (P < 0.01), according to "Treatment of ocular itching associated with ocular demodicosis by 5% tea tree oil ointment" by Gao YY, Xu DL, Huang J, Wang R, Tseng SC.(8)

9. Methicillin-resistant Staphylococcus aureus
In the review of tea tree oil is capable of killing methicillin-resistant Staphylococcus aureus (MRSA) in a laboratory setting, found that researched the effectiveness of tea tree oil preparations against MRSA. One small RCT (n = 30) showed a large but non-significant improvement at eradicating MRSA compared to traditional treatment, whereas a larger study (n = 224) demonstrated little difference in rates of eradication overall (41% for tea tree and 49% for mupirocin, p = 0.286). However, the larger study found that those with nasal colonization receiving a tea tree regimen were more likely to remain colonized with MRSA in the nose, according to "Is tea tree oil effective at eradicating MRSA colonization? A review" by

Flaxman D, Griffiths P.(9)

10. Etc.

Soybean Health Benefits and Side Effects

Soybean is the genus Glycine, belonging to the family Fabaceae, one of the legumes that contains twice as much protein per acre as any other major vegetable or grain crop, native to Southeast Asia. Now, it is grown worldwide with suitable climate for commercial profit and a a healthy foods. The herb has been used in traditional medicine for the proper functioning of the bowels, heart, kidney, liver, stomach. etc.

Health benefits
A. Health Benefits according to studies
1. Insulin sensitive
Soybean helps to normalize plasma glucose and insulin homeostasis, according to "Increased insulin sensitivity and changes in the expression profile of key insulin regulatory genes and beta cell transcription factors in diabetic KKAy-mice after feeding with a soy bean protein rich diet high in isoflavone content" by Nordentoft I, Jeppesen PB, Hong J, Abudula R, Hermansen K.(1)

2. Cardiovascular diseases
Soy protein reduces reduces the levels of serum lipoprotein, decrease in low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), LDL-C/high-density lipoprotein cholesterol (HDL-C), triacylglycerol/HDL-C and TC/HDL-Cpostmenopausal women are at risk of cardiovascular disease, according to "Effects of soy bean on serum paraoxonase 1 activity and lipoproteins in hyperlipidemic postmenopausal women" by Shidfar F, Ehramphosh E, Heydari I, Haghighi L, Hosseini S, Shidfar S.(2)

3. Adipogenesis and Adipolysis
Germinated soy bean protein hydrolysates had an effect on inhibition of lipid storage in adypocites and increasing lipolysis, according to "Effect of Germinated Soybean Protein Hydrolysates on Adipogenesis and Adipolysis in 3T3-L1 Cells" by González-Espinosa de Los Monteros LA, Ramón-Gallegos E, Torres-Torres N, Mora-Escobedo R.(3)

4. Antioxidant effects
Extract from Virginia-grown soybean seeds had exerted its antioxidant effect when compared for their total phenolic contents (TPC), oxygen radical absorbance capacity (ORAC), and 2,2-diphenyl-1-picrylhydrazyl radical (DPPH(*)) scavenging activities, according to "Comparison of different strategies for soybean antioxidant extraction" by Chung H, Ji X, Canning C, Sun S, Zhou K.(4)

5. Diabetes and hypertension
Soybean phenolic-rich extracts has exerted the inhibitory activities of phenolic-rich extracts from soybean on α-amylase, α-glucosidase and angiotensin I converting enzyme (ACE) activities in vitro, according to "Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro" by Ademiluyi AO, Oboh G.(5)

6. Aspartic acid
Aspartic acid not only helps to protect the body from drug toxicity and radiation, it also plays an essential role for the brain in information transmitting across the synapse, thus enhancing the learning and memory mechanism, according to the study of "Disinhibition-Mediated LTP in the Hippocampus is Synapse Specific" by Ormond J, Woodin MA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21954377

7. Histidine
Histidine plays an important role in promoting white and red blood cells, thus increasing the immune system in fight against forming of free radical and reducing the risk anemia., according to the study of "The role of histidine in the anemia of folate deficiency" by Cooperman JM, Lopez R., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/12486209), researchers concluded that concluded that folate deficiency causes histidine depletion through increased urinary excretion of this amino acid. Feeding histidine replenishes tissue levels of histidine, resulting in hemoglobin regeneration. Folic acid administration results in return of histidine to normal urinary levels. Thus, a combination of folic acid histidine would be beneficial for folate deficient individuals.

8. Serine
As an amino acid, serine in soybean not only helps to maintain proper muscle build up by synthesizing fatty acids and proteins, it also is important for brain in to transport information between themselves and cells in other parts of the body, according to the study of "Transport systems of serine at the brain barriers and in brain parenchymal cells" by Kasai Y, Tachikawa M, Hirose S, Akanuma S, Hosoya K., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21592122)

9. Alanine
Alanine not only is essential in production of energy in glucose synthesis (according to the study ofGlucose and insulin effects on the novo amino acid synthesis in young men: studies with stable isotope labeled alanine, glycine, leucine, and lysine" by Robert JJ, Bier DM, Zhao XH, Matthews DE, Young VR., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/6815417) it also enhances the immune system in production of anti bodies., according to the study of "The immune response of tetraparental mice to two synthetic amino acid polymers: "high-conjugation" 2,4 dinitrophenyl-glutamic acid57-lysine38-alanine5 (DNP-GLA5) and glutamic acid60 alanine30 tyrosine10 (GAT10)" by Warner CM, Fitzmaurice M, Maurer PH, Merryman CF, Schmerr MJ., posted in The Journey of Immunology (http://www.jimmunol.org/content/111/6/1887)

10. Isoleucine
Another animo acid helps to maintain the body tissues and store glycogen in muscles thereby reducing the risk of muscle breaking down during physical activity., according to the study of "Isoleucine, a potent plasma glucose-lowering amino acid, stimulates glucose uptake in C2C12 myotubes" by Doi M, Yamaoka I, Fukunaga T, Nakayama M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/14651987), researchers that isoleucine stimulates the insulin-independent glucose uptake in skeletal muscle cells, which may contribute to the plasma glucose-lowering effect of isoleucine in normal rats.

11. Etc.

Side effect
1. Toxicity
Raw soybeans, including the immature green form, are toxic.
2. Etc.

Healthy Happy Herbs
A Beginner's Guide To Herbs And
Herb Gardening, Step by step

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

For the world most popular herbs list, visit http://theworldmostpopularherbs.blogspot.com/2011/10/world-most-popular-herbs-health.html
other health articles, please visit http://medicaladvisorjournals.blogspot.com

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/18522411
(2) http://www.ncbi.nlm.nih.gov/pubmed/18608549
(3) http://www.ncbi.nlm.nih.gov/pubmed?term=Effect%20of%20Germinated%20Soybean%20Protein%20Hydrolysates%20on%20Adipogenesis%20and%20Adipolysis%20in%203T3-L1%20Cells
(4) http://www.ncbi.nlm.nih.gov/pubmed/20302378
(5) http://www.ncbi.nlm.nih.gov/pubmed/22005499

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Sunday, January 15, 2012